Article
Hyper-phosphorylation of nsp2-related proteins of porcine reproductive and respiratory syndrome virus.
Virology - 1 Apr 2020
Shang Pengcheng, Yuan Fangfeng, Misra Saurav, Li Yanhua, Fang Ying
Abstract excerpt
Viruses exploit phosphorylation of both viral and host proteins to support viral replication. In this study, we demonstrate that porcine reproductive and respiratory syndrome virus replicase nsp2, and two nsp2-related -2/-1 frameshifting products, nsp2TF and nsp2N, are hyper-phosphorylated. By mapping phosphorylation sites, we subdivide an extended, previously uncharacterized region, located between the...
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