Article
Genetic determinants of circulating VEGF levels in major depressive disorder and electroconvulsive therapy response.
Drug development research - 1 Aug 2020
Maffioletti Elisabetta, Gennarelli Massimo, Magri Chiara, Bocchio-Chiavetto Luisella, Bortolomasi Marco, Bonvicini Cristian, Abate Maria, Trabucchi Luigi, Ulivi Sheila, Minelli Alessandra
Abstract excerpt
Alterations in peripheral vascular endothelial growth factor (VEGF) levels were observed in major depressive disorder and relative treatments and were shown to be influenced by genetic variants. The study objective was to explore, at a genome-wide level, possible interplaying effects between the genetic background and major depressive disorder in regulating VEGF levels. Moreover, we aimed to investigate the...
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