Article
Gene expression and association analysis of vascular endothelial growth factor in major depressive disorder.
Progress in neuro-psychopharmacology & biological psychiatry - 13 Apr 2007
Iga Jun-Ichi, Ueno Shu-Ichi, Yamauchi Ken, Numata Shusuke, Tayoshi-Shibuya Sumiko, Kinouchi Sawako, Nakataki Masahito, Song Hongwei, Hokoishi Kazuhiko, Tanabe Hirotaka, Sano Akira, Ohmori Tetsuro
Abstract excerpt
Vascular endothelial growth factor (VEGF) has been implicated in neuronal survival, neuroprotection, regeneration, growth, differentiation, and axonal outgrowth, which are known to be involved in the pathophysiology of major depressive disorder (MDD). Recently, the VEGF mRNA expression in the peripheral leukocytes from Alzheimer's disease or cardiovascular disease was reported to be changed. We hypothesized that...
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