Article
Defining the metabolic signatures associated with human macrophage polarisation.
Biochemical Society transactions - 31 Aug 2023
Povo-Retana Adrián, Landauro-Vera Rodrigo, Fariñas Marco, Sánchez-García Sergio, Alvarez-Lucena Carlota, Marin Silvia, Cascante Marta, Boscá Lisardo
Abstract excerpt
Macrophages are essential components of the innate immune system that play both homeostatic roles in healthy organs, and host defence functions against pathogens after tissue injury. To accomplish their physiological role, macrophages display different profiles of gene expression, immune function, and metabolic phenotypes that allow these cells to participate in different steps of the inflammatory reaction, from...
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