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Article

Abnormal keratinization and cutaneous inflammation in Mal de Meleda.

The Journal of dermatology - 1 May 2020

Kudo Mari, Ishiura Nobuko, Tamura-Nakano Miwa, Shimizu Teruo, Kamata Masahiro, Akasaka Eijiro, Nakano Hajime, Okuma Yoshiaki, Tada Yayoi, Okochi Hitoshi, Tamaki Takeshi

Abstract excerpt

Mal de Meleda (MDM) is a rare, autosomal recessive form of palmoplantar keratoderma due to mutations in the gene, encoding for secreted lymphocyte antigen 6/urokinase-type plasminogen activator receptor related protein 1 (SLURP1). We report a four-year-old Taiwanese MDM female case whose biopsy specimen of hyperkeratotic lesions showed abnormal keratinization and cutaneous inflammation with characteristic...

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Identifiers

PMID: 32157724
DOI: 10.1111/1346-8138.15296

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Abnormal keratinization and cutaneous inflammation in Mal de Meleda.PMID 32157724Read ↗

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