Article
Mal de Meleda: A Focused Review.
American journal of clinical dermatology - 1 Feb 2016
Perez Caroline, Khachemoune Amor
Abstract excerpt
Mal de Meleda is a rare autosomal recessive palmoplantar keratoderma (PPK) disease with an estimated prevalence of 1:100,000. Clinically, the onset of the disease is typically soon after birth and features a transgrediens (plantar surface progressing to dorsal surface) and progrediens (worsening with age) pattern of hyperkeratosis of the palms and soles. The disease can feature other potentially disfiguring...
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