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Article

An integrative analysis of 5HTT-mediated mechanism of hyperactivity to non-threatening voices.

Communications biology - 10 Mar 2020

Chen Chenyi, Martínez Róger M, Liao Tsai-Tsen, Chen Chin-Yau, Yang Chih-Yung, Cheng Yawei

Abstract excerpt

The tonic model delineating the serotonin transporter polymorphism's (5-HTTLPR) modulatory effect on anxiety points towards a universal underlying mechanism involving a hyper-or-elevated baseline level of arousal even to non-threatening stimuli. However, to our knowledge, this mechanism has never been observed in non-clinical cohorts exhibiting high anxiety. Moreover, empirical support regarding said association...

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Identifiers

PMID: 32157156
DOI: 10.1038/s42003-020-0850-3
PMCID: PMC7064530

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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