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Article

Cancer Mutations: Molecular MEKanisms.

Current biology : CB - 9 Mar 2020

Bardwell Lee

Abstract excerpt

MEK, a central component of the Ras/MAPK cascade, is mutated in human tumors and developmental disorders. Recent studies are beginning to dissect the mechanisms that make these MEK mutants hyperactive.

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Identifiers

PMID: 32155425
DOI: 10.1016/j.cub.2020.01.039

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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