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Distinct expression and prognostic value of members of SMAD family in non-small cell lung cancer.

Medicine - 1 Mar 2020

Zeng Zhenguo, Yang Yuting, Qing Cheng, Hu Zhiguo, Huang Yiming, Zhou Chaoqi, Li Dan, Jiang Yanxia

Abstract excerpt

Non-small cell lung cancer (NSCLC) is the major cause of cancer mortality worldwide. Though multidisciplinary therapies have been widely used for NSCLC, its overall prognosis remains very poor, presumably owing to lack of effective prognostic biomarkers. SMAD, a well-known transcription factor, plays an essential role in carcinogenesis. Aberrant expression of SMAD have been found in various cancers, and may be...

Topics

Apoptosis Regulatory Proteins
Asian People
Biomarkers, Tumor
Carcinoma, Non-Small-Cell Lung
China
Data Mining
Databases, Factual
Gene Expression Regulation, Neoplastic
Genetic Predisposition to Disease
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lung Neoplasms

Mitochondrial Proteins

Prognosis

RNA, Messenger

Survival Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 32150102
DOI: 10.1097/MD.0000000000019451
PMCID: PMC7220383

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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