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Article

Whole exome sequencing analysis of urine trans-renal tumour DNA in metastatic colorectal cancer patients.

ESMO open - 1 Nov 2019

Crisafulli Giovanni, Mussolin Benedetta, Cassingena Andrea, Montone Monica, Bartolini Alice, Barault Ludovic, Martinetti Antonia, Morano Federica, Pietrantonio Filippo, Sartore-Bianchi Andrea, Siena Salvatore, Di Nicolantonio Federica, Marsoni Silvia, Bardelli Alberto, Siravegna Giulia

Abstract excerpt

BACKGROUND: The analysis of circulating free tumour DNA (ctDNA) in blood, commonly referred as liquid biopsy, is being used to characterise patients with solid cancers. Tumour-specific genetic variants can also be present in DNA isolated from other body fluids, such as urine. Unlike blood, urine sampling is non-invasive, can be self-performed, and allows recurrent longitudinal monitoring. The features of tumour...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32149725
DOI: 10.1136/esmoopen-2019-000572
PMCID: PMC7001107

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