Article
Recurrent Oncogenic JAK and STAT Alterations in Cutaneous CD30-Positive Lymphoproliferative Disorders.
The Journal of investigative dermatology - 1 Oct 2020
Maurus Katja, Appenzeller Silke, Roth Sabine, Brändlein Stephanie, Kneitz Hermann, Goebeler Matthias, Rosenwald Andreas, Geissinger Eva, Wobser Marion
Abstract excerpt
The group of cutaneous CD30-positive lymphoproliferative disorders (LPD) comprises two different entities, namely lymphomatoid papulosis (LyP) and cutaneous anaplastic large T-cell lymphoma (cALCL). LyP constitutes a benign lymphoproliferation with spontaneously regressing papules, whereas cALCL presents with solitary or multiple skin tumors with a low propensity to disseminate. To elucidate the hitherto largely...
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