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Differential metabolic and hepatic transcriptome responses of two miniature pig breeds to high dietary cholesterol.

Life sciences - 1 Jun 2020

Cai Zhaowei, Yu Chen, Fu Danting, Pan Yongming, Huang Junjie, Rong Yili, Deng Liqun, Chen Jiaojiao, Chen Minli

Abstract excerpt

AIMS: Pigs are increasingly used as human metabolic disease models; however, there is insufficient research on breed-related genetic background differences. This study aimed to investigate the differential metabolic responses to high-fat and high-cholesterol (HFC) diet-induced non-alcoholic fatty liver disease (NAFLD) of two miniature pig breeds and explore the molecular mechanisms involved. MAIN METHODS: Male...

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Animal Feed
Cholesterol, Dietary
Diet, High-Fat
Hypercholesterolemia
Hyperlipidemias

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Swine, Miniature

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PMID: 32145306
DOI: 10.1016/j.lfs.2020.117514

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