Article
The expression signatures in liver and adipose tissue from obese Göttingen Minipigs reveal a predisposition for healthy fat accumulation.
Nutrition & diabetes - 23 Mar 2020
Cirera Susanna, Taşöz Emirhan, Juul Jacobsen Mette, Schumacher-Petersen Camilla, Østergaard Christoffersen Berit, Kaae Kirk Rikke, Pagh Ludvigsen Trine, Hvid Henning, Duelund Pedersen Henrik, Høier Olsen Lisbeth, Fredholm Merete
Abstract excerpt
BACKGROUND: Model animals are valuable resources for dissecting basic aspects of the regulation of obesity and metabolism. The translatability of results relies on understanding comparative aspects of molecular pathophysiology. Several studies have shown that despite the presence of overt obesity and dyslipidemia in the pig key human pathological hepatic findings such as hepatocellular ballooning and abundant...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.