Article
A gene-diet interaction-based score predicts response to dietary fat in the Women's Health Initiative.
The American journal of clinical nutrition - 1 Apr 2020
Westerman Kenneth, Liu Qing, Liu Simin, Parnell Laurence D, Sebastiani Paola, Jacques Paul, DeMeo Dawn L, Ordovás José M
Abstract excerpt
BACKGROUND: Although diet response prediction for cardiometabolic risk factors (CRFs) has been demonstrated using single genetic variants and main-effect genetic risk scores, little investigation has gone into the development of genome-wide diet response scores. OBJECTIVE: We sought to leverage the multistudy setup of the Women's Health Initiative cohort to generate and test genetic scores for the response of 6...
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