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Article

A simplified qPCR method revealing tRNAome remodeling upon infection by genotype 3 hepatitis E virus.

FEBS letters - 1 Jun 2020

Ou Xumin, Ma Buyun, Zhang Ruyi, Miao Zhijiang, Cheng Anchun, Peppelenbosch Maikel P, Pan Qiuwei

Abstract excerpt

The landscape of tRNA-viral codons regulates viral adaption at the translational level, presumably through adapting to host codon usage or modulating the host tRNAome. We found that the major zoonotic genotype of hepatitis E virus (HEV) has not adapted to host codon usage, prompting exploration of the effects of HEV infection on the host tRNAome. However, tRNAome quantification is largely impeded by the extremely...

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PMID: 32133647
DOI: 10.1002/1873-3468.13764

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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