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Biomarkers for Early Cancer Diagnosis: Prospects for Success through the Lens of Tumor Genetics.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Apr 2020

Dragani Tommaso A, Matarese Valerie, Colombo Francesca

Abstract excerpt

Thousands of candidate cancer biomarkers have been proposed, but so far, few are used in cancer screening. Failure to implement these biomarkers is attributed to technical and design flaws in the discovery and validation phases, but a major obstacle stems from cancer biology itself. Oncogenomics has revealed broad genetic heterogeneity among tumors of the same histology and same tissue (or organ) from different...

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PMID: 32128843
DOI: 10.1002/bies.201900122

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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