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Article

Changes in pregnancy-related serum biomarkers early in gestation are associated with later development of preeclampsia

3 Mar 2020

Abstract excerpt

BACKGROUND: Placental protein expression plays a crucial role during pregnancy. We hypothesized that: (1) circulating levels of pregnancy-associated, placenta-related proteins throughout gestation reflect the temporal progression of the uncomplicated, full-term pregnancy, and can effectively estimate gestational ages (GAs); and (2) preeclampsia (PE) is associated with disruptions in these protein levels early in...

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PMID: 32126118
DOI: 10.1371/journal.pone.0230000

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