Article
Rethinking Risk Prediction in Preeclampsia: From Biomarkers to Mechanistic Phenotypes and Longitudinal Models.
International journal of molecular sciences - 13 Apr 2026
Espino-Y-Sosa Salvador, Moreno-Verduzco Elsa Romelia, Monroy-Muñoz Irma Eloisa, Solis-Paredes Juan Mario, Pérez Durán Javier, Rojas Zepeda Lourdes, Torres-Torres Johnatan
Abstract excerpt
Preeclampsia remains a major cause of maternal and perinatal morbidity and mortality worldwide, yet progress in biomarker discovery and predictive modeling has translated only modestly into clinically meaningful risk stratification. Over the past two decades, numerous biomarkers and predictors reflecting placental-angiogenic dysfunction, maternal cardiovascular maladaptation, and inflammatory-metabolic stress...
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