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Article

Effects of Tooth Loss and the Apolipoprotein E ɛ4 Allele on Mild Memory Impairment in the Fujiwara-kyo Study of Japan: A Nested Case-Control Study.

Journal of Alzheimer's disease : JAD - 1 Jan 2017

Okamoto Nozomi, Morikawa Masayuki, Amano Nobuko, Yanagi Motokazu, Takasawa Shin, Kurumatani Norio

Abstract excerpt

BACKGROUND: Several studies have suggested that periodontal disease can exacerbate the pro-inflammatory status of the brain. Tooth loss is one of the alternative evaluation indices of periodontal disease. There are few data on the relationship between tooth loss and memory impairment, depending on the apolipoprotein E (APOE) ɛ4 genotype. OBJECTIVE: To determine if tooth loss is associated with mild memory...

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Identifiers

PMID: 27716671
DOI: 10.3233/JAD-160638
PMCID: PMC5147497

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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