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Article

Dawn of a New RAMPage.

Trends in pharmacological sciences - 1 Apr 2020

Serafin D Stephen, Harris Natalie R, Nielsen Natalie R, Mackie Duncan I, Caron Kathleen M

Abstract excerpt

Receptor activity-modifying proteins (RAMPs) interact with G-protein-coupled receptors (GPCRs) to modify their functions, imparting significant implications upon their physiological and therapeutic potentials. Resurging interest in identifying RAMP-GPCR interactions has recently been fueled by coevolution studies and orthogonal technological screening platforms. These new studies reveal previously unrecognized...

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Identifiers

PMID: 32115276
DOI: 10.1016/j.tips.2020.01.009
PMCID: PMC7236817

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