Article
Domain I of hepatitis C virus NS5A associates with ACBD3 in a genotype-dependent manner.
Microbiology and immunology - 1 Aug 2020
Lu Yue, Yang Xiaojie, Zhang Leiliang
Abstract excerpt
Previously, it was found that the hepatitis C virus NS5A interacted with ACBD3 in a genotype-dependent manner. However, the region in NS5A responsible for association with ACBD3 is not clear. Domain I of NS5A was identified as critical for ACBD3 binding. By comparing the differences of amino acids in domain I from different genotypes of NS5A, it was found that key amino acids potentially corresponded to the...
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