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Article

Nix-Mediated Mitophagy Modulates Mitochondrial Damage During Intestinal Inflammation

27 Feb 2020

Abstract excerpt

Aims: Mitochondrial stress and dysfunction within the intestinal epithelium are known to contribute to the pathogenesis of inflammatory bowel disease (IBD). However, the importance of mitophagy during intestinal inflammation remains poorly understood. The primary aim of this study was to investigate how the mitophagy protein BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like (BNIP3L/NIX) mitigates...

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PMID: 32103677
DOI: 10.1089/ars.2018.7702

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