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Article

Long-term Consequences of Pelvic Irradiation: Toxicities, Challenges, and Therapeutic Opportunities with Pharmacologic Mitigators.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jul 2020

Huh Jung Wook, Tanksley Jarred, Chino Junzo, Willett Christopher G, Dewhirst Mark W

Abstract excerpt

A percentage of long-term cancer survivors who receive pelvic irradiation will develop treatment-related late effects, collectively termed pelvic radiation disease. Thus, there is a need to prevent or ameliorate treatment-related late effects in these patients. Modern radiotherapy methods can preferentially protect normal tissues from radiation toxicities to permit higher doses to targets. However, concerns about...

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PMID: 32098770
DOI: 10.1158/1078-0432.CCR-19-2744

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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