Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polypharmacy to Mitigate Acute and Delayed Radiation Syndromes

17 May 2021

Abstract excerpt

There is a need for countermeasures to mitigate lethal acute radiation syndrome (ARS) and delayed effects of acute radiation exposure (DEARE). In WAG/RijCmcr rats, ARS occurs by 30-days following total body irradiation (TBI), and manifests as potentially lethal gastrointestinal (GI) and hematopoietic (H-ARS) toxicities after >12.5 and >7 Gy, respectively. DEARE, which includes potentially lethal lung and kidney...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chemotherapy-induced cardiotoxicity and mitigation
Share to Effects of Radiation Exposure

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 34079456
DOI: 10.3389/fphar.2021.634477

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polypharmacy to Mitigate Acute and Delayed Radiation SyndromesPMID 34079456Read ↗

Establishing a Murine Model of the Hematopoietic Syndrome of the Acute Radiation SyndromeSemantic proximity Read ↗

Thrombopoietin mimetic stimulates bone marrow vascular and stromal niches to mitigate acute radiation syndromeSemantic proximity Read ↗

Effects of captopril against radiation injuries in the Göttingen minipig model of hematopoietic-acute radiation syndromeSemantic proximity Read ↗

Effect of Age at Time of Irradiation, Sex, Genetic Diversity, and Granulopoietic Cytokine Radiomitigation on Lifespan and Lymphoma Development in Murine H-ARS Survivors.Semantic proximity Read ↗

Mitigative efficacy of the clinical dosage administration of granulocyte colony-stimulating factor and romiplostim in mice with severe acute radiation syndromeSemantic proximity Read ↗

Immune system phenotyping of radiation and radiation combined injury in outbred mice.Semantic proximity Read ↗

Anti-ceramide single-chain variable fragment mitigates radiation GI syndrome mortality independent of DNA repairSemantic proximity Read ↗

Ionizing radiation-induced risks to the central nervous system and countermeasures in cellular and rodent modelsSemantic proximity Read ↗

Impact of Abbreviated Filgrastim Schedule on Survival and Hematopoietic Recovery after Irradiation in Four Mouse Strains with Different RadiosensitivitySemantic proximity Read ↗

Pharmacological Countermeasures for the Acute Radiation SyndromeSemantic proximity Read ↗

Age and Sex Divergence in Hematopoietic Radiosensitivity in Aged Mouse Models of the Hematopoietic Acute Radiation SyndromeSemantic proximity Read ↗

MIIST305 mitigates gastrointestinal acute radiation syndrome injury and ameliorates radiation-induced gut microbiome dysbiosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.