Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

AGAP2: Modulating TGFβ1-Signaling in the Regulation of Liver Fibrosis

19 Feb 2020

Abstract excerpt

AGAP2 (Arf GAP with GTP-binding protein-like domain, Ankyrin repeat and PH domain 2) isoform 2 is a protein that belongs to the Arf GAP (GTPase activating protein) protein family. These proteins act as GTPase switches for Arfs, which are Ras superfamily members, being therefore involved in signaling regulation. Arf GAP proteins have been shown to participate in several cellular functions including membrane...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Liver physiology and pathology
Share to Protein Kinase Regulation and GTPase Signaling
Share to TGF-β signaling in diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32092977
DOI: 10.3390/ijms21041400

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

AGAP2: Modulating TGFβ1-Signaling in the Regulation of Liver FibrosisPMID 32092977Read ↗

RASGRP2 is a potential immune-related biomarker and regulates mitochondrial-dependent apoptosis in lung adenocarcinomaSemantic proximity Read ↗

Fibroblast‐specific adipocyte enhancer binding protein 1 is a potential pathological trigger and prognostic marker for liver fibrosis independent of etiologySemantic proximity Read ↗

SAA1/TLR2 axis directs chemotactic migration of hepatic stellate cells responding to injurySemantic proximity Read ↗

Time-course RNA sequencing reveals high similarity in mRNAome between hepatic stellate cells activated by agalactosyl IgG and TGF-β1Semantic proximity Read ↗

MeCP2 controls the expression of RASAL1 in the hepatic fibrosis in ratsSemantic proximity Read ↗

Comprehensive analysis on the whole Rho‐GAP family reveals that ARHGAP4 suppresses EMT in epithelial cells under negative regulation by Septin9Semantic proximity Read ↗

The Controversial Role of Retinoic Acid in Fibrotic Diseases: Analysis of Involved Signaling PathwaysSemantic proximity Read ↗

Signaling pathways of PAX2 and its role in renal interstitial fibrosis and glomerulosclerosis.Semantic proximity Read ↗

FOSL2 participates in renal fibrosis via SGK1-mediated epithelial-mesenchymal transition of proximal tubular epithelial cellsSemantic proximity Read ↗

Fibroblast Activation Protein Alpha (FAPα) in Fibrosis: Beyond a Perspective Marker for Activated Stromal Cells?Semantic proximity Read ↗

Lysophosphatidic acid signaling through its receptor initiates profibrotic epithelial cell fibroblast communication mediated by epithelial cell derived connective tissue growth factor.Semantic proximity Read ↗

Increased PDGFRalpha activation disrupts connective tissue development and drives systemic fibrosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.