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Article

Loss of SMARCB1 expression in colon carcinoma

18 Feb 2020

Abstract excerpt

SMARCB1 is a tumor suppressor gene, which is part of SWI/SNF complex involved in transcriptional regulation. Recently, loss of SMARCB1 expression has been reported in gastrointestinal carcinomas. Our purpose was to evaluate the incidence and prognostic value of SMARCB1 loss in colon carcinoma (CC). Patients with stage III CC (n= 1695), and a second cohort of 23 patients with poorly differentiated CC were...

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PMID: 32083567
DOI: 10.3233/cbm-190287

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