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Article

Novel Strain of the Chronic Wasting Disease Agent Isolated From Experimentally Inoculated Elk With LL132 Prion Protein.

Scientific reports - 21 Feb 2020

Moore Jo, Tatum Trudy, Hwang Soyoun, Vrentas Catherine, West Greenlee M Heather, Kong Qingzhong, Nicholson Eric, Greenlee Justin

Abstract excerpt

Chronic wasting disease (CWD) is a fatal, progressive disease that affects cervid species, including Rocky mountain elk (Cervus elaphus nelsoni). There are 2 allelic variants in the elk prion protein gene: L132 (leucine) and M132 (methionine). Following experimental oral challenge with the CWD agent incubation periods are longest in LL132 elk, intermediate in ML132 elk, and shortest in MM132 elk. In order to...

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Identifiers

PMID: 32081886
DOI: 10.1038/s41598-020-59819-1
PMCID: PMC7035384

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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