Article
Uncovering the genetic landscape for multiple sleep-wake traits.
PloS one - 1 Jan 2009
Winrow Christopher J, Williams Deanna L, Kasarskis Andrew, Millstein Joshua, Laposky Aaron D, Yang He S, Mrazek Karrie, Zhou Lili, Owens Joseph R, Radzicki Daniel, Preuss Fabian, Schadt Eric E, Shimomura Kazuhiro, Vitaterna Martha H, Zhang Chunsheng, Koblan Kenneth S, Renger John J, Turek Fred W
Abstract excerpt
Despite decades of research in defining sleep-wake properties in mammals, little is known about the nature or identity of genes that regulate sleep, a fundamental behaviour that in humans occupies about one-third of the entire lifespan. While genome-wide association studies in humans and quantitative trait loci (QTL) analyses in mice have identified candidate genes for an increasing number of complex traits and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.