Comprehensive pharmacogenomic characterization of gastric cancer.

doi:10.1186/s13073-020-0717-8

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Article

Comprehensive pharmacogenomic characterization of gastric cancer.

Genome medicine - 18 Feb 2020

Sa Jason K, Hong Jung Yong, Lee In-Kyoung, Kim Ju-Sun, Sim Moon-Hee, Kim Ha Jung, An Ji Yeong, Sohn Tae Sung, Lee Joon Ho, Bae Jae Moon, Kim Sung, Kim Kyoung-Mee, Kim Seung Tae, Park Se Hoon, Park Joon Oh, Lim Ho Yeong, Kang Won Ki, Her Nam-Gu, Lee Yeri, Cho Hee Jin, Shin Yong Jae, Kim Misuk, Koo Harim, Kim Mirinae, Seo Yun Jee, Kim Ja Yeon, Choi Min-Gew, Nam Do-Hyun, Lee Jeeyun

Abstract excerpt

BACKGROUND: Gastric cancer is among the most lethal human malignancies. Previous studies have identified molecular aberrations that constitute dynamic biological networks and genomic complexities of gastric tumors. However, the clinical translation of molecular-guided targeted therapy is hampered by challenges. Notably, solid tumors often harbor multiple genetic alterations, complicating the development of...

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PMID: 32070411
DOI: 10.1186/s13073-020-0717-8
PMCID: PMC7029441

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