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Article

Tenascin-C expression controls the maturation of articular cartilage in mice.

BMC research notes - 17 Feb 2020

Gruber Bastian L, Mienaltowski Michael J, MacLeod James N, Schittny Johannes, Kasper Stephanie, Flück Martin

Abstract excerpt

OBJECTIVE: Expression of the de-adhesive extracellular matrix protein tenascin-C (TNC) is associated with the early postnatal development of articular cartilage which is both load-dependent and associated with chondrocyte differentiation. We assessed morphological changes in the articular cartilage of TNC deficient mice at postnatal ages of 1, 4 and 8 weeks compared to age-matched wildtype mice. RESULTS:...

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Identifiers

PMID: 32066496
DOI: 10.1186/s13104-020-4906-8
PMCID: PMC7027060

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