Article
ASXL1 mutations, previous vascular complications and age at diagnosis predict survival in 85 WHO-defined polycythaemia vera patients.
British journal of haematology - 1 Jun 2020
Andréasson Björn, Pettersson Helna, Wasslavik Carina, Johansson Peter, Palmqvist Lars, Asp Julia
Abstract excerpt
Polycythaemia vera (PV) patients have an overall comparatively favourable prognosis, but disease progression is very heterogeneous and life-threatening thrombosis and bleedings are frequent complications in untreated disease. Moreover, transformation to more severe secondary myelofibrosis and acute myeloid leukaemia can occur. The aim of this study was to identify gene mutations that could be used together with...
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