Article
Succinate dehydrogenase gene mutations in cardiac paragangliomas.
The American journal of cardiology - 15 Jun 2015
Martucci Victoria L, Emaminia Abbas, del Rivero Jaydira, Lechan Ronald M, Magoon Bindiya T, Galia Analyza, Fojo Tito, Leung Steve, Lorusso Roberto, Jimenez Camilo, Shulkin Barry L, Audibert Jennifer L, Adams Karen T, Rosing Douglas R, Vaidya Anand, Dluhy Robert G, Horvath Keith A, Pacak Karel
Abstract excerpt
Pheochromocytomas and paragangliomas are chromaffin cell tumors arising from neuroendocrine cells. At least 1/3 of paragangliomas are related to germline mutations in 1 of 17 genes. Although these tumors can occur throughout the body, cardiac paragangliomas are very rare, accounting for <0.3% of mediastinal tumors. The purpose of this study was to determine the clinical characteristics of patients with cardiac...
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