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Article

Association of the FGFR1 mutation with spontaneous hemorrhage in low-grade gliomas in pediatric and young adult patients.

Journal of neurosurgery - 1 Mar 2021

Ishi Yukitomo, Yamaguchi Shigeru, Hatanaka Kanako C, Okamoto Michinari, Motegi Hiroaki, Kobayashi Hiroyuki, Terasaka Shunsuke, Houkin Kiyohiro

Abstract excerpt

OBJECTIVE: The authors aimed to investigate genetic alterations in low-grade gliomas (LGGs) in pediatric and young adult patients presenting with spontaneous hemorrhage. METHODS: Patients younger than 30 years of age with a pathological diagnosis of World Health Organization (WHO) grade I or II glioma and who had undergone treatment at the authors' institution were retrospectively examined. BRAF V600E, FGFR1...

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Identifiers

PMID: 32059187
DOI: 10.3171/2019.12.JNS192155

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