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Article

A Comprehensive Examination of the Role of Epigenetic Factors in Multiple Sclerosis.

International journal of molecular sciences - 16 Aug 2024

Manna Ida, De Benedittis Selene, Porro Danilo

Abstract excerpt

According to various research, the risk of multiple sclerosis (MS) is strongly influenced by genetic variations. Population, familial, and molecular studies provide strong empirical support for a polygenic pattern of inheritance, mainly due to relatively common allelic variants in the general population. The strongest MS susceptibility locus, which was unmistakably identified in tested populations, is the major...

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Identifiers

PMID: 39201606
DOI: 10.3390/ijms25168921
PMCID: PMC11355011

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