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Article

Cytochrome P450 4B1 (CYP4B1) as a target in cancer treatment

13 Feb 2020

Abstract excerpt

Cytochrome P450 4B1 (CYP4B1) plays crucial roles in biotransforming of xenobiotics. Its predominant extrahepatic expression has been associated with certain tissue-specific toxicities. However, the expressions of CYP4B1 in various cancers and hence their potential roles in cancer development were inclusive. In this work, existing knowledge on expression and regulation of CYP4B1 gene and protein, catalysis of...

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PMID: 32054340
DOI: 10.1177/0960327120905959

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