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Article

Development of molecularly targeted therapies in biliary tract cancers: reassessing the challenges and opportunities.

Hepatology (Baltimore, Md.) - 1 Feb 2011

Zhu Andrew X, Hezel Aram F

Abstract excerpt

Biliary tract cancers (BTCs), which encompass intra- and extrahepatic cholangiocarcinomas as well as gallbladder carcinomas, are a genetically diverse collection of cancers. Most patients with BTC will present with unresectable or metastatic disease. Although the standard systemic chemotherapy approaches are emerging, the prognosis remains poor. Development of molecularly targeted therapies in advanced BTC...

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Identifiers

PMID: 21274890
DOI: 10.1002/hep.24145

Genes

BTC

Provenance

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