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Article

Distinct host-immune response toward species related intracellular mycobacterial killing: A transcriptomic study

13 Feb 2020

Abstract excerpt

The comparison of the host immune response when challenged with pathogenic and nonpathogenic species of mycobacteria can provide answers to the unresolved question of how pathogens subvert or inhibit an effective response. We infected human monocyte derived macrophages (hMDMs) with different species of mycobacteria, in increasing order of pathogenicity, i.e. M. smegmatis, M. bovis BCG, and M. tuberculosis R179...

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PMID: 32052695
DOI: 10.1080/21505594.2020.1726561

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