Article
Antiviral activity of curcumin-nanoemulsion associated with photodynamic therapy in vulvar cell lines transducing different variants of HPV-16.
Artificial cells, nanomedicine, and biotechnology - 1 Dec 2020
Bonfim Caroline Measso do, Monteleoni Letícia Figueiredo, Calmon Marília de Freitas, Cândido Natália Maria, Provazzi Paola Jocelan Scarin, Lino Vanesca de Souza, Rabachini Tatiana, Sichero Laura, Villa Luisa Lina, Quintana Silvana Maria, Melli Patrícia Pereira Dos Santos, Primo Fernando Lucas, Amantino Camila Fernanda, Tedesco Antonio Claudio, Boccardo Enrique, Rahal Paula
Abstract excerpt
Vulvar intraepithelial neoplasia (VIN) is associated with human papillomavirus (HPV) infection. Curcumin is a natural bioactive compound with antineoplastic properties. The use of nanoparticles containing curcumin could allow a better performance of this compound in therapies. So, VIN biopsies were collected and HPV DNA detection was performed by PCR, positive samples were genotyped by Restriction Fragment Length...
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