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Article

The role of environmental stress and DNA methylation in the longitudinal course of bipolar disorder

12 Feb 2020

Abstract excerpt

Abstract Background Stressful life events influence the course of affective disorders, however, the mechanisms by which they bring about phenotypic change are not entirely known. Methods We explored the role of DNA methylation in response to recent stressful life events in a cohort of bipolar patients from the longitudinal PsyCourse study (n = 96). Peripheral blood DNA methylomes were profiled at two time points...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32048126
DOI: 10.1186/s40345-019-0176-6

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