Article
Anti-Müllerian Hormone Regulates Stem Cell Factor via cAMP/PKA Signaling Pathway in Human Granulosa Cells by Inhibiting the Phosphorylation of CREB.
Reproductive sciences (Thousand Oaks, Calif.) - 1 Jan 2020
Fu Yun-Xing, Wang Fei-Miao, Ou-Yang Xiao-E, Yang Hui-Min, Hu Ting, Wang Ya-Fei, Wang Yan-Fei, Wang Hui, Hu Rong
Abstract excerpt
Anti-Müllerian hormone (AMH) downregulates the level of stem cell factor (SCF) via the cAMP/PKA signaling pathway in human granulosa cells (GCs). Little information is available on the molecular mechanism underlying the interaction. This study is aimed at determining whether AMH regulates expression of SCF via the cAMP-PKA-CREB signaling pathway in human GCs. In the present study, we verified the binding of...
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