Article
Association between IL17 polymorphisms and risk of cervical cancer in Chinese women.
Clinical & developmental immunology - 1 Jan 2012
Quan Yi, Zhou Bin, Wang Yanyun, Duan Ruiqi, Wang Kana, Gao Qianqian, Shi Shaoqing, Song Yaping, Zhang Lin, Xi Mingrong
Abstract excerpt
Interleukin-17 (IL-17) is a proinflammatory cytokine that is associated with inflammation, autoimmune disorders, and even tumors. Previous studies revealed that a large group of human malignant tumors have abnormally high IL-17 expression. In the present study, we analyzed two single-nucleotide polymorphisms (SNPs) in the IL17A (rs2275913) and IL17F (rs763780) in 311 cervical cancer patients and 463 controls...
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