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The hipBAXn operon from Xenorhabdus nematophila functions as a bonafide toxin-antitoxin module.

Applied microbiology and biotechnology - 1 Apr 2020

Yadav Mohit, Rathore Jitendra Singh

Abstract excerpt

Here, for the first time, we have investigated the hipBAXn toxin-antitoxin (TA) module from entomopathogenic bacterium Xenorhabdus nematophila. It is a type II TA module that consists of HipAXn toxin and HipBXn antitoxin protein and located in the complementary strand of chromosome under XNC1_operon 0810 locus tag. For functional analysis, hipAXn toxin, hipBXn antitoxin, and an operon having both genes were...

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PMID: 32043192
DOI: 10.1007/s00253-020-10441-1

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