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Article

Hha toxin regulates diverse phenotypes of uropathogenic Proteus mirabilis including virulence.

Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi - 1 Feb 2026

Chao Yueh-Jung, Lee Yuan-Ju, Chen Hsuan-Hsuan, Kao Cheng-Yen, Liaw Shwu-Jen

Abstract excerpt

BACKGROUND: To disclose Proteus mirabilis copper detoxification mechanisms, we performed Tn5-mutagenesis and an hha gene-disrupted mutant was isolated, exhibiting increased copper sensitivity. We investigated the role of Hha in P. mirabilis, focusing on the virulence aspects. METHODS: Assays of copper susceptibility, swarming/swimming, biofilm formation, persister cell formation, killing by macrophages, adhesion,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40897649
DOI: 10.1016/j.jmii.2025.08.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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