Article
Rapid inference of antibiotic resistance and susceptibility by genomic neighbour typing.
Nature microbiology - 1 Mar 2020
Břinda Karel, Callendrello Alanna, Ma Kevin C, MacFadden Derek R, Charalampous Themoula, Lee Robyn S, Cowley Lauren, Wadsworth Crista B, Grad Yonatan H, Kucherov Gregory, O'Grady Justin, Baym Michael, Hanage William P
Abstract excerpt
Surveillance of drug-resistant bacteria is essential for healthcare providers to deliver effective empirical antibiotic therapy. However, traditional molecular epidemiology does not typically occur on a timescale that could affect patient treatment and outcomes. Here, we present a method called 'genomic neighbour typing' for inferring the phenotype of a bacterial sample by identifying its closest relatives in a...
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