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Article

Gene profiling of canine B-cell lymphoma reveals germinal center and postgerminal center subtypes with different survival times, modeling human DLBCL.

Cancer research - 15 Aug 2013

Richards Kristy L, Motsinger-Reif Alison A, Chen Hsiao-Wei, Fedoriw Yuri, Fan Cheng, Nielsen Dahlia M, Small George W, Thomas Rachael, Smith Chris, Dave Sandeep S, Perou Charles M, Breen Matthew, Borst Luke B, Suter Steven E

Abstract excerpt

Diffuse large B-cell lymphoma (DLBCL) is the most common lymphoma subtype, and fewer than half of patients are cured with standard first-line therapy. To improve therapeutic options, better animal models that accurately mimic human DLBCL (hDLBCL) are needed. Canine DLBCL, one of the most common cancers in veterinary oncology, is morphologically similar to hDLBCL and is treated using similar chemotherapeutic...

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Share to Germinal Center
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Lymphoma, B-Cell

Share to Lymphoma, Large B-Cell, Diffuse

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Share to Proto-Oncogene Proteins c-bcl-6

Source

Open in PubMed Open full text

Identifiers

PMID: 23783577
DOI: 10.1158/0008-5472.CAN-12-3546
PMCID: PMC3755352

Genes

BCL6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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