The algorithm used for the interpretation of doravirine transmitted drug resistance strongly influences clinical practice and guideline recommendations.

doi:10.1093/jac/dkaa009

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Article

The algorithm used for the interpretation of doravirine transmitted drug resistance strongly influences clinical practice and guideline recommendations.

The Journal of antimicrobial chemotherapy - 1 May 2020

Guerrero-Beltrán Carlos, Martínez-Sanz Javier, Álvarez Marta, Olalla Julián, García-Álvarez Mónica, Iribarren Jose Antonio, Masiá Mar, Montero Marta, García-Bujalance Silvia, Blanco José Ramón, Rivero María, García-Fraile Lucio Jesús, Espinosa Núria, Rodríguez Carmen, Aguilera Antonio, Vidal-Ampurdanes María Carmen, Martínez Marina, Iborra Asunción, Imaz Arkaitz, Gómez-Sirvent Juan Luis, Peraire Joaquim, Portilla Joaquín, Caballero Estrella, Alejos Belén, García Federico, Moreno Santiago

Abstract excerpt

OBJECTIVES: We report the results of the reverse transcriptase (RT)/protease (PR) transmitted drug resistance (TDR) prevalence study in 2018, focusing on doravirine resistance-associated mutations and the differences observed when Stanford or French National Agency for AIDS Research (ANRS)/Spanish Network of AIDS Research (RIS)/IAS-USA resistance interpretation algorithms are used to describe clinically relevant...

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PMID: 32030406
DOI: 10.1093/jac/dkaa009

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