Prevalence of doravirine-associated resistance mutations in HIV-1-infected antiretroviral-experienced patients from two large databases in France and Italy.

doi:10.1093/jac/dkz553

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Prevalence of doravirine-associated resistance mutations in HIV-1-infected antiretroviral-experienced patients from two large databases in France and Italy.

The Journal of antimicrobial chemotherapy - 1 Apr 2020

Soulie Cathia, Santoro Maria Mercedes, Storto Alexandre, Abdi Basma, Charpentier Charlotte, Armenia Daniele, Jary Aude, Forbici Federica, Bertoli Ada, Gennari William, Andreoni Massimo, Mussini Cristina, Antinori Andrea, Perno Carlo Federico, Calvez Vincent, Ceccherini-Silberstein Francesca, Descamps Diane, Marcelin Anne-Genevieve

Abstract excerpt

OBJECTIVES: Doravirine, a novel NNRTI, selects for specific mutations in vitro, including mutations at reverse transcriptase (RT) positions 106, 108, 188, 227, 230 and 234. The aim of this study was to examine the prevalence of doravirine-associated resistance mutations in HIV-1-infected antiretroviral-experienced patients. METHODS: Doravirine-associated resistance mutations identified in vitro or in vivo were...

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PMID: 31976534
DOI: 10.1093/jac/dkz553

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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