Ancestry specific associations of FTO gene variant and metabolic syndrome: A longitudinal ARIC study.

doi:10.1097/MD.0000000000018820

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Ancestry specific associations of FTO gene variant and metabolic syndrome: A longitudinal ARIC study.

Medicine - 1 Feb 2020

Hardy Dale S, Garvin Jane T, Mersha Tesfaye B, Racette Susan B

Abstract excerpt

Cross-sectional studies indicate that the fat mass and obesity-associated (FTO) rs9939609 gene variant is associated with metabolic syndrome (MetS) primarily in European ancestry. However, the association is not fully elucidated in African Americans.We hypothesized that rs9939609 (AT = moderate-risk carriers or AA = high-risk carriers compared to TT = low-risk carriers) is associated with MetS and its component...

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Alpha-Ketoglutarate-Dependent Dioxygenase FTO
Black or African American

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PMID: 32028392
DOI: 10.1097/MD.0000000000018820
PMCID: PMC7015559

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