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Article

Interaction of FTO and physical activity level on adiposity in African-American and European-American adults: the ARIC study.

Obesity (Silver Spring, Md.) - 1 Sept 2011

Demerath Ellen W, Lutsey Pam L, Monda Keri L, Linda Kao Wen Hong, Bressler Jan, Pankow James S, North Kari E, Folsom Aaron R

Abstract excerpt

Physical inactivity accentuates the association of variants in the FTO locus with obesity-related traits but evidence is largely lacking in non-European populations. Here we tested the hypothesis that physical activity (PA) modifies the association of the FTO single-nucleotide polymorphism (SNP) rs9939609 with adiposity traits in 2,656 African Americans (AA) (1,626 women and 1,030 men) and 9,867 European...

Topics

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Adiposity
Alpha-Ketoglutarate-Dependent Dioxygenase FTO
Black or African American

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sex Characteristics

Waist Circumference

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Open in PubMed Open full text

Identifiers

PMID: 21593801
DOI: 10.1038/oby.2011.131
PMCID: PMC3293392

Genes

FTO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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Interaction of FTO and physical activity level on adiposity in African-American and European-American adults: the ARIC study.PMID 21593801Read ↗

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.Semantic proximity Read ↗

Physical activity attenuates the effect of the FTO genotype on obesity traits in European adults: The Food4Me study.Semantic proximity Read ↗

Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children.Semantic proximity Read ↗

Physical activity and FTO genotype by physical activity interactive influences on obesity.Semantic proximity Read ↗

The fat-mass and obesity-associated (FTO) gene, physical activity, and risk of incident cardiovascular events in white women.Semantic proximity Read ↗

Physical Activity and Insulin Sensitivity Independently Attenuate the Effect of FTO rs9939609 on Obesity.Semantic proximity Read ↗

FTO variant rs9939609 is associated with body mass index and waist circumference, but not with energy intake or physical activity in European- and African-American youthSemantic proximity Read ↗

Physical activity attenuates the body mass index-increasing influence of genetic variation in the FTO gene.Semantic proximity Read ↗

The interaction between FTO rs9939609 and physical activity is associated with a 2-fold reduction in the risk of obesity in Korean population.Semantic proximity Read ↗

Ancestry specific associations of FTO gene variant and metabolic syndrome: A longitudinal ARIC study.Semantic proximity Read ↗

FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals.Semantic proximity Read ↗

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