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[Clinical Characteristics and Prognosis of U2AF1 Mutation in Patients with Acute Myeloid Leukemia].

Zhongguo shi yan xue ye xue za zhi - 1 Feb 2020

Zhao Ting-Yuan, Guan Li-Xun, Zheng Wen-Shuai, Wang Mei-Lu, Cheng Long-Can, Hu Ya-Lei, Xu Yuan-Yuan, Gu Zhen-Yang, Dou Li-Ping

Abstract excerpt

OBJECTIVE: To investigate the incidence, clinical features of U2AF1 gene mutation in patients with acute myeloid leukemia(AML) and its effect of prognosis. METHODS: A total of 161 patients with AML were enrolled. The second-generation sequencing method was used to detect U2AF1 gene mutation, and the relationship between U2AF1 mutation and clinical features, prognosis was analyzed. RESULTS: The mutation rate of...

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Identifiers

PMID: 32027245
DOI: 10.19746/j.cnki.issn.1009-2137.2020.01.002

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